目的 分析医院药师关于患者出院带抗肿瘤药安全性的知识、态度及实践,探究可能存在的风险因素,为有针对性的开展肿瘤患者出院用药指导及合理用药提供参考。方法 于2019年3月15日至2019年5月31日对中国31个省(市)各级医院的药师进行关于患者出院带抗肿瘤药安全性的问卷调查。结果 药师抗肿瘤药相关知识的平均得分为46.7,相当于总分的51.8％。多数药师(74.5%)知晓出院带抗肿瘤药存在风险,并愿意(93.9%)为肿瘤患者提供用药指导。然而,药师对出院肿瘤患者的指导多局限于口头交代(62.1%),出院后患者求助医务人员的可及性普遍偏低(55.6%)。结论 用药安全参与人员对患者出院带抗肿瘤药的安全风险重视不足、医院药师关于抗肿瘤药知识储备存在短板、患者用药教育没有完善的管理制度等均是威胁肿瘤患者出院后用药的风险因素。应认真寻找解决办法,不断提升患者出院带抗肿瘤药的安全性。
Abstract
OBJECTIVE To analyze the knowledge, attitude and practice of hospital pharmacists on the safety of patients with anti-tumor drugs discharged from hospitals, explore possible risk factors, and provide reference for targeted guidance and rational medication of tumor patients discharged. METHODS From March 15, 2019 to May 31, 2019, pharmacists at hospitals in 31 provinces (cities) in China conducted a questionnaire survey on the safety of patients with anti-tumor drugs discharged from hospitals. RESULTS The average score of pharmacists′ knowledges of anti-tumor drugs was 46.7, equivalent to 51.8% of the total score. Most pharmacists (74.5%) are aware of the risks of discharge of antineoplastic agents and are willing (93.9%) to provide medication guidance for cancer patients. However, the pharmacists′ guidance for patients with cancer on the discharge was mostly limited to oral presentation (62.1%), and the accessibility of pharmacists to cancer patients after discharge was generally low (55.6%). CONCLUSION Drug safety participants pay insufficient attention to the safety risks of patients with anticancer drugs discharged, and hospital pharmacists′ knowledge reserve of anti-tumor drugs has shortcomings, there is no perfect system of medication education for discharged patients, which are all risk factors threatening the safety of medication for cancer patients after discharge. Serious efforts should be made to find solutions to continuously improve the safety of patients with anticancer drugs discharged from hospitals.
关键词
医院药师 /
知识-态度-行为模式 /
出院带药 /
抗肿瘤药物 /
风险因素 /
用药安全
{{custom_keyword}} /
Key words
hospital pharmacist /
KAP /
discharge medication /
anti-tumor drug /
risk factor /
medication safety
{{custom_keyword}} /
中图分类号：
R951
{{custom_clc.code}}
({{custom_clc.text}})
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] SHENG Y Q, LI Q H, WANG Y, et al. Comprehensive intervention before and after drug use to promote clinical rational use of tumor therapy adjuvant drugs[J]. Pharm Clin Res, 2019, 27(3):237-240.
[2] CAO M M, CHEN W Q. Epidemiology of cancer in China and the current status of prevention and control[J]. Chin J Clin Oncol(中国肿瘤临床), 2019, 46(3):145-149.
[3] GLOBOCAN. Population Fact Sheets[EB/OL]. GLOBOCAN, (2019-05) [2019-08-03]. https://gco.iarc.fr/today/data/factsheets/populations/160-china-fact-sheets.pdf.
[4] GAO F, TENG F, LIANG H, et al. Postdischarge care guidance needs of cancer patients[J]. Chin J Clin Oncol Rehabil, 2019, 26(4):498-501.
[5] MA Y Q. Statistics on the discharge of drugs in the department of oncology and the drug education of clinical pharmacists on discharged patients[J]. Mod Med J China(中国现代医药), 2018, 20(3):77-79.
[6] CPA. The pharmacy professional committee of China pharmaceutical association continues to promote high-risk drug management and risk prevention [EB/OL]. CPA, (2019-07-08) [2019-08-03]. http://www.cpa.org.cn/?do=info&cid=75014.
[7] HESHMAT R, SALEHI F, QORBANI M, et al. Economic inequality in nutritional knowledge, attitude and practice of Iranian households: the NUTRI-KAP study[J]. Med J Islam Repub Iran, 2016,30(1):426.
[8] GUO W. Effect of KAP nursing program on postoperative quality of life and gastrointestinal function in patients undergoing colon cancer surgery[J]. Chin General Pract Nur(全科护理), 2019, 17(18):2186-2188.
[9] FAN Q Q, LI Q Y, ZHU Z, et al. Risk analysis from exploratory survey on knowledge, attitude and practice (KAP) towards medication safety among Beijing residents[J]. Chin J Drug Appl Monitor(中国药物应用与临床), 2018, 15(6):368-371.
[10] HONGYAN L, XIANGLONG X, DENGYUAN L, et al. Nutrition-related knowledge, attitudes, and practices (KAP) among kindergarten teachers in Chongqing, China: a cross-sectional survey[J]. Inter J Environmental Res Public Health, 2018, 15(4):615.
[11] CHEN C Y, CHEN P J. Production of emergency kit for chemotherapeutic drug spillover treatment[J]. Global Tradit Chin Med, 2015, 8(S1):138.
[12] CONNOR T, MCLAUCHLAN R, VANDENBROUCKE J. ISOPP Standards of practice. Safe handling of cytotoxics[J]. J Oncol Pharm Pract, 2007, 13(suppl):1-81.
[13] WANG H Y, XU R, HUANG J L, et al. New practice upon continuous quality management of antineoplastic agents in hospital[J]. Anti-tumor Pharm, 2019, 9(1):139-142.
{{custom_fnGroup.title_cn}}
脚注
{{custom_fn.content}}
基金
中华医学会临床药学分会-吴阶平医学基金会科研专项基金项目资助(320.6750.19090-30)
{{custom_fund}}
PDF(4785 KB)
